Development and qualification of 4-plex assay for AAV vector genome integrity evaluation by dPCR
The production of viral vectors for gene therapy is focused on pure, safe, and efficacious products. Absence of impurities and presence of full vector genomes play a crucial role. We
Multiplex dPCR and SV-AUC are Promising Assays to Robustly Monitor the Critical Quality Attribute of AAV Drug Product Integrity
Article published on ScienceDirect by David Dobnik, CSO and David B. Hayes
Measuring Viral Titer in AAV-Mediated Gene Therapy Using a PCR Technique for Absolute Quantitation
Article published on BioProcess International by David Dobnik, CSO.